This is a relatively rare tumor that most surgeons will not find in their careers 8 , and the fact that the case presented here is that of a male patient reinforces its unusual nature All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. In view of these findings, we think that there is still a lack of knowledge about the diagnosis of AA among the clinicians. Unusual Abdominal and Pelvic Tumors. Accordingly, she was referred to our clinic because of surgical failure.

In light of current knowledge, the role of hormonal therapy in the management of this particular tumor remains to be determined 5. It is likely due to the loose myxoid matrix and high-water content of AA [ 8 ]. Case Presentation A year-old nulliparous female patient with a previous history of left femoral hernia operation was admitted to our hospital. This has created some controversy over whether surgical margins are associated with recurrence, but the results of these reports have not been possible to reproduce 2, Cir Esp ; 84 2:

Further evidence is required to establish the true value of this treatment. It is important to differentiate angiomyxoma from angiomyofibroblastoma of the vulva which shares histogenic features with it.

Report of a Case and Review of the Literature. The patient should be informed about the high morbidity of the surgical intervention. There have been no reports of metastasis among men to date Moreover, the optimal duration of therapy is unknown.

Aggressive angiomyxoma: a case series and literature review.

Incidence and reports of the disease have been increasing each year Aggressive Angiomyxoma of the Male Genital Region. The tumor was completely excised by sharp and blunt dissection Figure 2. However, there are series of cases which have reported no differences in rates of recurrence among patients with negative surgical margins and those with positive margins.


Since tumors are usually large, contiguous involvement of several sites is common 5. In the present patient, AA was misdiagnosed as incarcerated femoral hernia and the patient underwent emergent surgery which resulted in surgical failure.

These cases are very common, and often unexpected. Embolization of the tumor has been reported as an alternative approach; however, it remains insufficient due to the extensive vascular network of the tumor. Lesions disappear or their size, as measured clinically seriez with imaging, decreases within three months to a year.

aggressive angiomyxoma a case series and literature review

Histopathologic examination of the tumor. Nevertheless, it has been suggested that it can be used for evaluation of margins and in the detection of small foci of residual tumor excisions or recurrences.

aggressive angiomyxoma a case series and literature review

Both of these radiological features are secondary to the loose myxoid matrix and high water content of these lesions 2, 6, 9, Management requires complete removal of the lesion and the clinical and imaging follow-up given their high rate of recurrence. While aggerssive age distribution has a wide range, it occurs most frequently between ages 18 and 63 afgressive peak incidence during the reproductive years from the second to fourth decades of life.

Digital examination of the rectum was normal. The tumor has exerted pressure on the bladder, the left ureter, uterus, and left iliac vein. It is noteworthy that there is still a lack of knowledge about the clinical presentation, the management options, and the follow-up results of AA literaturee the current literature.

Aggressive angiomyxoma in men: Clinical case report and literature review

A year-old female patient who previously underwent surgery for left femoral hernia operation resulting in surgical failure was reoperated for a giant AA located in the pelvis. It is most frequently found in the scrotum, perineum, groin, pelvis and spermatic cord 1. All adjacent organs and pelvic vessels were depressed by the mass. During the dissection, no infiltration into the adjacent organs was detected except a partial invasion into the left external iliac vein.


Long-term follow-up and careful monitoring are essential due to its high tendency of local recurrence in spite of wide excision of the tumor. It is hard to define the exact incidence of AA among the other intra-abdominal mesenchymal tumors because of its rarity.

Aggressive angiomyxoma: a case series and literature review.

Results depend on the size of the lesion and on whether it is a primary or secondary tumor. The mitotic activity was not observed. Soft tissue aggressive angiomyxoma is associated with a high risk of local recurrence after removal, but metastasis is almost unheard of.

Subscribe to Table of Contents Alerts. According to our view, reporting case series of these tumors may lead to a better understanding of how AA behaves. FOLLOW-UP Follow-up examinations at intervals of one to two years in which ultrasound and Aangiomyxoma examinations are alternated are sufficient, given the slow growth and low likelihood of metastasis of this tumor 3.

Nevertheless, there have been reports aggreesive recurrences occurring up to 17 years after initial surgery.